Chemical group BASF reports that a new plastic film, for which a patent has been applied, will protect its pharmaceuticals excipient polyvinylpyrrolidone (PVP) even better against the penetration of atmospheric oxygen and thus against oxidation.
“With this product, BASF will be able to offer the pharmaceuticals industry a better product quality and, as a result, improved patient safety,” says BASF global business management for PVP Dr Boris Jenniches.
The company reports that its products, processes and facilities exceed the strict international quality standards of the pharmaceuticals industry. Consequently, independent institute the United States Pharmacopeia (USP) has certified the PVP produced by BASF. The USP not only inspected compliance with the requirements of current good manufacturing practice, but also the quality and the documentation of production control and quality control.
Simultaneously, the PVP marketed by BASF was also certified for the European market in a wide-ranging good-manu- facturing practice audit. “Aware-ness of the need for quality of pharmaceutical ingredients has been growing steadily. BASF guarantees a consistently high product quality and in this way contributes to the success of its pharmaceuticals customers,” says Jenniches.
Under the registered trade name Kollidon, PVP is used in tablets as a binding agent and disintegrant. As a binding agent, it enables the individual active ingredients of a tablet to form a homogenous entity and, as a disintegrator, it ensures that tablets break up in a liquid and release the active ingredient quickly.
PVP has a success story that spans about 70 years, after it was patented in 1939. It is soluble in water but can also absorb large quantities of water; and is not irritating to the skin, is not a potential health hazard and it is temperature resistant, pH stable, nonionic and colourless. Owing to these varied features, it is used in various BASF product lines, including those for the cosmetics, detergent and food industries.
Meanwhile, the company also launched its new polyurethane solutions brand late last year.
The branding aims to emphasise customer focus, innovation, flexibility, consulting and problem- solving expertise and excellent product quality from a global network of more than 35 BASF system houses.
“It gives customers all over the world access to BASF’s expertise, problem-solving skills and extensive presence in many key industries,” says BASF polyurethane division head Jacques Delmoitiez.
Polyurethanes are used in a vast range of products. BASF reports that polyurethanes enable architects to design buildings with better insulation and allow car manufacturers to build more attractive and lighter- weight vehicles.